OpenFOAM Simulations of Late Stage Container Draining in Microgravity

OpenFOAM Container in the UberCloud

Numerical Simulations of Phase Change in Microgravity

Direct numerical simulations of liquid-solid and liquid-vapor phase change are conducted under microgravity conditions. The time-dependent governing equations are solved using a two-dimensional nitedi erence/front-tracking method. Large interface deformations, topology change, latent heat, surface tension and unequal material properties between the phases are included in the simulations. Result...

Towards Large Scale Packed Bed Chromatography Simulations with OpenFOAM R ©

Column liquid chromatography (CLC) is a widely used unit operation in biotech and chemical process engineering for purification of target products (e.g. proteins for pharmaceutical agents) from unwanted substances. An aqueous solution containing the mixture of molecules is forced to flow through the chromatography column which is filled with porous particles (beads). While transport through the...

Structural dynamics of possible late-stage intermediates in folding of quadruplex DNA studied by molecular simulations

Explicit solvent molecular dynamics simulations have been used to complement preceding experimental and computational studies of folding of guanine quadruplexes (G-DNA). We initiate early stages of unfolding of several G-DNAs by simulating them under no-salt conditions and then try to fold them back using standard excess salt simulations. There is a significant difference between G-DNAs with al...

Dynamic Mesh Handling in Openfoam Applied to Fluid-structure Interaction Simulations

The power of OpenFOAM [1] in physical modelling stems from mimicking of partial differential equations in software, thus allowing rapid and reliable implementation of complex physical models. State-of-the art complex geometry handling and dynamic mesh features are essential for practical engineering use. This paper describes features of dynamic mesh support in OpenFOAM. Polyhedral mesh handling...